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July 21, 2008 - 06:00 AM
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Gene Panel Predicts Lung Cancer Survival, Study Finds
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Researchers from four leading cancer centers have confirmed that an analysis involving a panel of genes can be used to predict which lung cancer patients will have the worst survival. The finding could one day lead to a test that would help determine who needs more aggressive treatment.
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July 14, 2008 - 11:00 AM
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Mobilizing White Blood Cells To The Lung: New Discovery Could Lead To An Improved Influenza Vaccine
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New findings shed new light on how a previously-unknown messaging mechanism within the human immune system prompts specific influenza-fighting cells to the lung airways during an infection. Although researchers have known for some time that white blood cells congregating in the lung and directly attacking the virus play an important role in defending against influenza, it has never been clear how exactly these white blood cells know when they are required in the lung.
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July 10, 2008 - 05:00 AM
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Higher Education Associated With Greater Gains In Mortality Reduction From Common Cancers
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Deaths due to the four most common cancers have dropped substantially in the US from 1993 to 2001 in working-aged individuals. However, not all Americans are equally likely to benefit from those gains. More educated individuals had mortality reductions in nearly all four cancers, while less educated individuals had a mortality reduction in only one cancer type.
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July 9, 2008 - 11:00 PM
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Aerosol Toxins From Red Tides May Cause Long-term Health Threat
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An algal toxin commonly inhaled in sea spray, attacks and damages DNA in the lungs of laboratory rats. The findings document how the body's way of disposing the toxin inadvertently converts it to a molecule that damages DNA. Human inhalation of brevetoxins produced by the red tide organism, Karenia brevis, is an increasing public health concern.
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July 8, 2008 - 11:00 AM
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MRI Technique To ID Microstructural Changes In Asthma
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Scientists have developed a novel magnetic resonance imaging (MRI) technique that -- for the first time ever -- identified microscopic structural damages deep in the lungs of patients with asthma.
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July 7, 2008 - 06:00 AM
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Guidelines For Care Of Elderly Patients Routinely Ignored, Study Shows
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Guidelines for the treatment of older patients with respiratory conditions are routinely ignored. Research shows that recommended treatments are given to only a small minority of eligible patients.
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July 7, 2008 - 06:00 AM
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Pediatricians Reluctant To Taper Medications In Kids With Stable Asthma
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A study of how pediatricians prescribe asthma medications suggests that while most would readily increase a child's medication if needed, many are reluctant to taper off drug use when less might be best.
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July 2, 2008 - 02:00 PM
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Finding That Could Shed Light On 'Golden Staph,' Candida And Allergies
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Recent scientific findings explain why patients with a rare immunodeficiency disorder are unusually susceptible to certain common infections. By revealing the exact molecular mechanisms involved, they also give us clues as to why some "healthy" people are more prone to these infections than others, and suggest potential treatments.
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June 30, 2008 - 11:00 AM
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Promising Finding In Severe Lung Disease
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Researchers have identified a novel function for an enzyme that plays a role in the tissue injury in acute respiratory distress syndrome, also known as ARDS.
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June 27, 2008 - 02:00 PM
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Faulty DNA Repair Could Be A Risk Factor For Lung Cancer In Nonsmokers
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People who have never smoked but whose cells cannot efficiently repair environmental insults to DNA are at higher risk of developing lung cancer than those with effective genomic repair capability.
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June 26, 2008 - 08:00 PM
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Intestinal Proteins May Be Effective Anti-Tumor Antigens
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Mice immunized with an intestinal protein developed fewer lung and liver metastases following injection with colon cancer cells than unvaccinated animals, according to a study in the June 24 issue of the Journal of the National Cancer Institute.
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June 26, 2008 - 05:00 PM
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Different Type Of Colon Cancer Vaccine Reduces Disease Spread, Scientists Show
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Taking advantage of the fact that the intestines have a separate immune system from the rest of the body, scientists have found a way to immunize mice against the development of metastasis. They have shown that mice immunized with an intestinal protein developed fewer lung and liver metastases after injection with colon cancer cells than did controls. The work may portend the development of a different kind of cancer vaccine that may help prevent recurrence.
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June 26, 2008 - 06:00 AM
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New Clinical Trial For Patients With Asbestos-associated Lung Cancer
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The Mesothelioma Center within the Herbert Irving Comprehensive Cancer Center at NewYork-Presbyterian Hospital and Columbia University Medical Center is now recruiting patients for a clinical research study of a new targeted radiation and chemotherapy protocol for pleural mesothelioma, a cancer of the lung's lining that is almost always caused by previous exposure to asbestos.
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June 25, 2008 - 02:00 AM
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Five Genes Identified In Metastasis Of Breast Tumors To The Lung
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Scientists have identified five genes involve in the metastasis of breast tumors to the lung. Of the five genes identified, the Tenascina-C gene seems to be a good therapeutic target for the treatment of metastatic breast cancer. In fact, the blocking of the expression of this gene in the animal model enabled a significant reduction, both in tumour growth and in the incidence of pulmonary metastasis.
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June 18, 2008 - 02:00 PM
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Key Developmental Pathway Activates Lung Stem Cells
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Researchers found that the activation of a molecular pathway important in stem cell and developmental biology leads to the increase in lung stem cells. Harnessing this knowledge could help develop therapies for lung-tissue repair after injury or disease.
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June 18, 2008 - 08:00 AM
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Ability To Track Stem Cells In Tumors Could Advance Cancer Treatments
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Using noninvasive molecular imaging technology, a method has been developed to track the location and activity of mesenchymal stem cells in the tumors of living organisms. This ability could lead to major advances in the use of stem cell therapies to treat cancer.
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June 16, 2008 - 06:00 AM
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New Test Could Aid Children Suffering From Reflux Disease
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A nuclear medicine imaging test was used to confirm that children with respiratory problems may be more likely to develop gastroesophageal reflux disease, according to researchers. The technique, known as scintigraphy, was also shown to be more effective in detecting the disease in these children than traditional barium X-ray technology and could become an important diagnostic tool for detecting reflux disease in children.
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June 15, 2008 - 02:00 AM
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Risk-of-death Charts By Age And Gender Updated
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Researchers have updated charts that show an American's risk of dying from a given cause over the next ten years, based on age, sex and smoking status. At all ages, men have a higher risk of death from all causes combined, relative to women. For both men and women, smoking increases the risk of death by nearly the same magnitude as adding approximately 5 years to a person's age.
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June 13, 2008 - 05:00 PM
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CT Lung Cancer Screening No Cure-all For Smokers
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Screening for lung cancer with computed tomography may help reduce lung cancer deaths in current and former smokers, but it won't protect them from other causes of death associated with smoking, according to a new study.
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June 12, 2008 - 11:00 AM
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TB Treatment For Elderly Likely Requires Boost To Immune Response
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Manipulating the immune system in elderly people appears to be the most likely way to help older patients wage an effective battle against tuberculosis, a new study suggests. Mathematical modeling of how mice respond to TB infection suggests that potential therapy options for elderly TB patients could either increase their white blood cell count or enhance infected cells' interaction with their immune system.
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June 10, 2008 - 11:00 PM
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Inhalable Form Of Gene-therapy Takes Aim At Lung Cancer And Inflammatory Lung Disease
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A new inhalable form of gene therapy -- based on technology recognized in the 2006 Nobel medicine prize, shows increasing promise for treating lung cancer, infectious diseases and inflammatory lung disease, scientists have concluded after an exhaustive review of worldwide research on the topic.
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June 10, 2008 - 08:00 AM
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Modified Surgical Technique Further Reduces Lung Surgery Pain
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A simple variation in a surgical technique to reduce acute and chronic pain following lung surgery further reduces pain and helps return patients to normal activity quicker than the previous technique.
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June 9, 2008 - 08:00 AM
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Why Diesel Particulates Cause Cardiovascular Disease
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A previously unknown mechanisms may explain why air pollution in the form of particulates causes heart attacks, stroke, and increasing mortality. Particulates in diesel exhaust are a substantial cause of the negative health effects traced to air pollution, above all in traffic environments. Diesel exhaust contains a number of extremely tiny particles about 1/10,000 mm in diameter, with chemical compounds bound to the surface that have been suggested to lie behind the ability of these particles to cause harmful health effects.
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June 5, 2008 - 02:00 PM
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UK Medics Solve Ancient Riddle Of 'Finger Clubbing'
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A puzzling medical condition, identified more than 2,000 years ago by Hippocrates, has finally been explained by researchers at the University of Leeds. The phenomenon of "finger clubbing", a deformity of the fingers and fingernails, has been known for thousands of years, and has long been recognized to be a sign of a wide range of serious diseases -- especially lung cancer.
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June 4, 2008 - 05:00 AM
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Gene Signature Profile For Metastasis Discovered
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Researchers have identified a common signature of tiny, specific pieces of non-coding genetic material known as microRNAs (miRNAs) that may be directly involved in the spread of cancer. The findings may represent a novel diagnostic tool in characterizing gene targets in metastatic cancer.
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June 3, 2008 - 08:00 PM
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More Girls Than Boys Benefit From Breastfeeding, Research Shows
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Challenging the long-standing belief that breast-feeding equally protects all babies against disease, new research suggests that when it comes to respiratory infections, the protective effects of breast milk are higher in girls than in boys.
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May 31, 2008 - 08:00 PM
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A New Way To Look At Lung Cancer And Tobacco Carcinogens
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Previous studies have shown how polycyclic aromatic hydrocarbons damage DNA, with the emphasis on how PAHs bind directly to DNA itself, leading to the mutations in critical genes that cause disease. Now, researchers have shown that PAHs, via oxidative stress, can also led to mutations in critical genes important in lung cancer.
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May 31, 2008 - 02:00 PM
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Fruits, Vegetables And Teas May Protect Smokers From Lung Cancer, Researchers Report
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Tobacco smokers who eat three servings of fruits and vegetables per day and drink green or black tea may be protecting themselves from lung cancer, according to a first-of-its-kind study by cancer researchers. The study is the first to find that plant components called flavonoids may prevent the disease.
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May 30, 2008 - 11:00 AM
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New Breathing Exercises Help Manage Asthma
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A presentation that demonstrates breathing exercises designed to help reduce the use of asthma inhalers is today available to the general public for free from the Cooperative Research Centre for Asthma and Airways website.
[Read more]
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May 29, 2008 - 08:00 PM
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Car Exhaust Therapy For Cardiopulmonary Bypass? A Poison As Protector
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A study in Anesthesiology could represent an important step toward the eventual use of carbon monoxide to promote cell survival and reduce lung inflammation in patients undergoing cardiopulmonary bypass surgery. Scientists used low doses of inhaled CO in pig models while employing beating-heart cardiopulmonary bypass surgery.
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May 28, 2008 - 05:00 AM
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Common Gene Disorder Doubles Risk Of Lung Cancer, Even Among Nonsmokers
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Researchers have found that carrying a common genetic disorder doubles the risk of developing lung cancer in smokers and nonsmokers.
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May 25, 2008 - 08:00 PM
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The Emerging Role Of Infection In Alzheimer's Disease
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A number of chronic diseases are in fact caused by one or more infectious agents. For example, stomach ulcers are caused by Helicobacter pylori, chronic lung disease in newborns and chronic asthma in adults are both caused by Mycoplasmas and Chlamydia pneumonia, while some other pathogens have been associated with atherosclerosis. The realization that pathogens can produce slowly progressive chronic diseases has opened new lines of research into Alzheimer's disease.
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May 24, 2008 - 08:00 PM
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Insights Into Lung Disease And Lung Function In Young Adults
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Two new studies provide insights into lung disease and lung function in young adults. One links low levels of a protein called adiponectin in fat cells to an increase in asthma risk in young women. A second finds that high levels of a protein called ICAM-1 is associated with lower lung function.
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May 23, 2008 - 08:00 PM
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Tuberculosis Not The Only Risk From New Immunological Drugs
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A new survey cautions physicians that drugs commonly prescribed for patients suffering from immunological disorders such as rheumatoid arthritis and inflammatory bowel disease may carry risks of serious infections other than the known risk of tuberculosis.
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May 23, 2008 - 05:00 PM
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New Treatment Gives Hope For Pulmonary Fibrosis Patients
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Patients with idiopathic pulmonary fibrosis may have a new treatment option, according to researchers in Japan. In a Phase III, double-blind, placebo-controlled clinical trial, the investigators discovered that a daily dose of pirfenidone could slow the progression of IPF, reducing the loss of lung capacity.
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May 23, 2008 - 02:00 AM
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Oxidative Stress May Predict Later Lung Trouble In Young Adults
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Markers of oxidative stress may predict future lung trouble, according to new research. Certain measures of oxidant stress are positively associated with declines in lung function five years down the road, and those declines are indicative of the possible onset of lung disease such as chronic obstructive pulmonary disease.
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May 21, 2008 - 11:00 PM
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Iraq War Service: A Risk Factor For Bronchiolitis?
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A large group of soldiers returning from Iraq have been diagnosed with bronchiolitis, a disease affecting the small airways of the lung. A total of 56 soldiers from Fort Campbell, Kentucky were evaluated for unexplained shortness of breath on exertion. Surgical lung biopsies were performed on 31 of the soldiers referred, with 29 having bronchiolitis. Most of those diagnosed with bronchiolitis had a prolonged exposure to sulfur dioxide from a sulfur mine fire near Mosul, Iraq in 2003, however, several had no known specific exposures.
[Read more]
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May 21, 2008 - 06:00 AM
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Low-intensity Case Management Cuts COPD-related Hospital Visits In Half
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A new study has found that patients with chronic obstructive pulmonary disease who are at high risk for hospitalization or emergency room visits from exacerbations or complications benefit from simple low-intensity case management.
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May 20, 2008 - 11:00 PM
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Will Lung Cancer Recur? A Genetic Test May Provide The Answer
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The goal of developing reliable genetic tests to guide lung cancer treatment has taken a step forward. Researchers recently evaluated the ability of five high-risk genetic profiles, or signatures, to predict the likelihood that cancer would recur in patients whose non-small cell lung cancer was caught early and surgically removed.
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May 20, 2008 - 08:00 PM
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Blood Test For Lung Cancer May Be Possible
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A simple blood test may be able to detect lung cancer in its earliest stages with unprecedented accuracy, according to new research. The possibility of developing a non-invasive test to distinguish cancerous from benign lesions in the lungs has enormous implications, not just for the world of medicine, but for every individual patient who has gone through the harrowing experience of having to wait for conclusive biopsy results after preliminary testing.
[Read more]
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May 20, 2008 - 06:00 AM
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Noninvasive Oxygen Therapy Eases Final Hours, Days For Lung Cancer Patients
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For patients with end-stage lung cancer, noninvasive ventilation may be more effective at reducing breathing difficulty than standard oxygen therapy, and has the added advantage of reducing patients' reliance on morphine, thus improving lucidity in their final days, according to new research. For patients at this stage, even small comforts can be the difference between a peaceful or an agonizing death.
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May 20, 2008 - 06:00 AM
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COPD Patients Benefit More From Pulmonary Rehabilitation In Earlier Stages
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Patients with chronic obstructive pulmonary disease who are in their final years of survival do not get the same benefits from pulmonary rehabilitation as patients who have more years left to live -- regardless of their age, complicating illnesses or lung function, according to new research.
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May 19, 2008 - 11:00 PM
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People With Obstructive Sleep Apnea At Risk For Cardiac Stress On Airline Flights
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People with severe obstructive sleep apnea on commercial airline flights may have a greater risk of adverse events from cardiac stress than healthy people, according to new research.
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May 19, 2008 - 08:00 AM
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Personalized Therapy For Asthma And COPD Could Soon Be Here
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Researchers have defined a new type of immune response that is activated in patients with severe asthma and COPD (chronic obstructive pulmonary disease). Their discovery could dramatically improve diagnosis and treatment of patients with chronic inflammatory lung disease.
[Read more]
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May 19, 2008 - 06:00 AM
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Pulmonary Rehab On Call: TELEHEALTH Offers Dial-up Help For The Rural And Remote
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A program that delivers pulmonary rehabilitation via video-conferencing technology, the internet and other emerging technologies to patients who live too far from respiratory therapy centers to make the twice-weekly trip improves their clinical condition, outcome and quality of life in just eight weeks, according to a new study.
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May 18, 2008 - 06:00 AM
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For Children With Sickle Cell Disease, Lung Disease Is Part Of The Package
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Children with sickle cell disease have a significantly sharper decline in lung function with age when compared to other children of the same race and age. Furthermore, that loss of function appears to be linked to a restrictive rather than obstructive pattern, contrary to previous research that has focused on obstructive or asthma-like patterns in loss of lung function with sickle cell disease.
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May 18, 2008 - 06:00 AM
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Depression And PTSD Symptoms In Caregivers Of Lung Transplant Patients
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Symptoms of depression and post-traumatic stress disorder among caregivers of deceased lung transplant patients are four-to-five times more prevalent than in the average population, according to researchers who analyzed the stress levels of caregivers, as well as their perceptions of the transplant recipients' quality of dying and death.
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May 16, 2008 - 06:00 AM
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Lung Cancer Patients Can Tolerate Post-surgery Exercise, And Can Benefit From It
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Patients who have undergone surgical procedures for the removal of lung cancer can tolerate and benefit from exercise regimens started just a month after surgery, according to a new study.
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